American Society for Clinical Pathology (ASCP) Technologist in Cytogenetics certification (ASCP CG) Practice Test

Choosing the Probe program when using the Applied Imaging system to capture the FISH image is appropriate because this program is specifically designed for fluorescence in situ hybridization (FISH) applications. The Probe function allows for optimal processing of fluorescent signals and is tailored for the specific requirements of capturing high-quality images related to cytogenetic analysis.

In the context of FISH, the Probe program provides analytical features that facilitate the identification of hybridization signals, which is essential for accurately assessing chromosomal abnormalities. This program enhances the detection capabilities and ensures that the images recorded reflect the true biological scenario being acted upon, which is critical for diagnostic accuracy.

In contrast, the other options serve different roles. The Analysis program typically focuses on post-capture image analysis and quantification, whereas Capture is intended more for the initial image acquisition without the FISH optimizations. The Preview option is generally used for checking the system setup and ensuring proper alignment before capture, but it does not actually take the image with the focused capabilities required for FISH. Thus, selecting the Probe program directly aligns with the needs of FISH imaging for cytogenetic evaluation.